Karisma RH COLLAGEN (1x2ml)


KARISMA is an innovative biostimulator based on type I collagen, obtained from silk threads, which naturally restores the skin’s firmness and elasticity.

KARISMA is indicated for the medium-term correction of facial skin defects due to skin aging and / or loss of volume, therefore suitable for those who wish to reduce skin imperfections of the face, lips, redefine the contours or in the which there is a particularly unstructured subcutaneous tissue. It is also able to correct small scarring (eg acne scars).



  • NATURAL – composed of totally natural substances and without the use of chemical binders,
  • BIOLOGICAL – totally biocompatible, it promotes the innate regenerative capacity of the skin,
  • SAFE – non allergenic, respectful of the natural origin of substances.


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    • rejuvenation of the skin of the face, mouth, neck, cleavage and hands,
    • improvement of the face contour, gentle lifting effect,
    • reduction of wrinkles,
    • reduction of scars and stretch marks,
    • improvement of the quality and density of the skin.

    Benefits of Karisma

    • better biocompatibility – it is identical with human collagen and immediately bioavailable, which gives results immediately after the treatment,
    • accelerates the multiplication of fibroblasts,
    • accelerates tissue regeneration,
    • perfect homogeneity – has controlled physical and rheological properties,
    • it is non-immunogenic, hypoallergenic and does not cause allergic reactions.


    High molecular weight hyaluronic acid with the addition of the R-polypeptide chain α1 and carboxymethylcellulose.


    • Rh Collagen – Combining collagen of the R-polypeptide chain α1 
      Increases the production of type I procollagen C-Peptide in fibroblasts. This type of peptides facilitate the wrapping of pro-collagen molecules in a triple helix conformation within the endoplasmic reticulum,
    • CMC – Carboxymethylcellulose
      It has an anti-aging effect in the dermis: it inhibits the action of the hyaluronidase enzyme and preserves the endogenous hyaluronic acid, which, while remaining in the tissues, continues to perform its hydration and tissue repair activity in depth,
    • HA – High molecular weight hyaluronic acid (1200-1500 kDa)
      It participates in the creation of a favorable environment for the proliferation and metabolism of fibroblasts.



    1 x 2ml prefilled syringe

    2 needles – 27G 13mm

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